17 Results for "

Clematis uncinata Champ.

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Clematis uncinata Champ." in MCE Product Catalog:

Humantenine
Humantenine
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Cat. No.: HY-N4031
CAS No.: 82375-29-9
Category:  

Alkaloids Other Diseases Loganiaceae Plants Gelsemium eleganis (Gardn. et Champ.) Benth. Disease Research Fields Indole Alkaloids

Target:  

Anaplastic lymphoma kinase (ALK) METTL3

Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
Cauloside F
Cauloside F
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Cat. No.: HY-N6265
CAS No.: 60451-47-0
Category:  

Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Terpenoids Other Diseases Plants Disease Research Fields Araliaceae

Target:  

Others

Cauloside F is a triterpenoid saponin isolated from Clematis akebioides.
Clematichinenoside AR
Clematichinenoside AR
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Cat. No.: HY-N4232
CAS No.: 761425-93-8
Category:  

Other Terpenoids Clematis chinensis Osbeck Terpenoids Ranunculaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Autophagy

Clematichinenoside AR is a major active ingredient that could be extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects on various diseases, including atherosclerosis (AS) .
Saponin CP6
Saponin CP6
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Cat. No.: HY-107235
CAS No.: 72629-76-6
Synonyms: Clematoside S; Prosapogenin CP6
Category:  

Triterpenes Terpenoids Ranunculaceae Other Diseases Plants Disease Research Fields Clematis grata Wall.

Target:  

Others

Saponin CP6 is a triterpenoid compound from the roots of Clematis grata .
KRAS G12C degrader-1
KRAS G12C degrader-1
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Cat. No.: HY-153881
CAS No.: 2768099-51-8
Target:  

Ras

Domaines de recherche:  

Cancer

KRAS G12C degrader-1 (Compound 283) is a potent KRAS G12C degrader (DC50: < 100 nM) for cancer research. KRAS G12C degrader-1 is a chaperone (HSP90)-mediated protein degrader (CHAMPs) .
CHAMP1 Human Pre-designed siRNA Set A
CHAMP1 Human Pre-designed siRNA Set A
Cat. No.: HY-RS02596
Target:  

Small Interfering RNA (siRNA)

Domaines de recherche:  

Others

CHAMP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHAMP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Huzhangoside D
Huzhangoside D
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Cat. No.: HY-107236
CAS No.: 96315-53-6
Category:  

Clematis graveolens Lindl. Triterpenes Terpenoids Ranunculaceae Other Diseases Plants Disease Research Fields

Target:  

Others

Huzhangoside D is a saponin compound isolated from the roots and rhizomes of Clematis graveolens .
Clematiganoside A
Clematiganoside A
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Cat. No.: HY-N11073
CAS No.: 1000293-05-9
Category:  

Triterpenes Clematis puberula var. anpiniana (H. Léveillé & Vaniot) W. T. Wang Terpenoids Ranunculaceae Plants

Target:  

Others

Clematiganoside A is a triterpenoid saponin that can be isolatred from Clematis ganpiniana .
Huzhangoside C
Huzhangoside C
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Cat. No.: HY-N11068
CAS No.: 96315-52-5
Category:  

Clematis uncinata Champ. Ranunculaceae Lignans Phenylpropanoids Plants

Target:  

Others

Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
3′,3′′′-Binaringenin
3′,3′′′-Binaringenin
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Cat. No.: HY-N9788
CAS No.: 145399-99-1
Category:  

Flavonoids Flavonones Selaginella uncinata (Desv.) Spring Selaginellaceae Plants

Target:  

Others

3′,3′′′-Binaringenin is a Flavonoids product that can be isolated from the herbs of Selaginella uncinata .
Clematomandshurica saponin C
Clematomandshurica saponin C
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Cat. No.: HY-N4229
CAS No.: 916649-92-8
Category:  

Triterpenes other families Terpenoids Other Diseases Plants Disease Research Fields

Target:  

Others

Clematomandshurica saponin C is found in Clematis manshurica .
Clematichinenoside C
Clematichinenoside C
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Cat. No.: HY-N5071
CAS No.: 177912-24-2
Category:  

Triterpenes Clematis parviloba Gard. et Champ. Terpenoids Ranunculaceae Other Diseases Plants Disease Research Fields

Target:  

Others

Clematichinenoside C is one of triterpenoid saponins found in Clematis parviloba .
trans-Isoferulic acid-d3
trans-Isoferulic acid-d3
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Cat. No.: HY-N0761AS
CAS No.: 1028203-97-5
trans-Isoferulic acid-d3 is the deuterium labeled trans-Isoferulic acid . trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .
trans-Isoferulic acid (Standard)
trans-Isoferulic acid (Standard)
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Cat. No.: HY-N0761AR
CAS No.: 25522-33-2
Synonyms: trans-3-Hydroxy-4-methoxycinnamic acid (Standard)
Category:  

Ketones, Aldehydes, Acids Ranunculaceae Plants

Target:  

Reference Standards NO Synthase Prostaglandin Receptor

trans-Isoferulic acid (Standard) is the analytical standard of trans-Isoferulic acid. This product is intended for research and analytical applications. trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity .trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1) .
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester
3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester
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Cat. No.: HY-N18269
CAS No.: 639515-41-6
Category:  

Terpenoids Ranunculaceae Clematis tangutica (Maxim.) Korsh. Plants Pentacyclic Triterpenoids

Target:  

Fungal

3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester is an anti-fungal triterpene saponin. 3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester can be isolated from the aerial parts of Clematis tangutica. 3-O-α-L-Arabinopyranosyl hederagenin 28-O-α-L-rhamnopyranosyl ester exhibits antifungal activity against fungal strains (P. avellaneum, C. glabrata, S. cerevisiae, T. beigelii), with the strongest activity against S. cerevisiae .
Protocatechuic acid-2-glucoside
Protocatechuic acid-2-glucoside
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Cat. No.: HY-N18300
CAS No.: 3056651-89-6
Category:  

Gentiana scabra Bunge Monophenols Gentianaceae Phenols Plants

Target:  

Others

Protocatechuic acid-2-glucoside (compound 6) is a phenolic acid glycoside. Protocatechuic acid-2-glucoside can be found in the rhizome and radix of Millettia speciosa Champ .
GB-1a
GB-1a
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Cat. No.: HY-136972A
CAS No.: 19360-72-6
Synonyms: Biflavanone GB-1a
Category:  

Flavonoids Plants Biflavones Anacardiaceae Toxicodendron vernicifluum (Stokes) F. A. Barkl.

Target:  

HIV Reverse Transcriptase

GB-1a (Biflavanone GB-1a) is a biflavanone HIV-1 reverse transcriptase inhibitor (IC50=236 μM), with an EC50 of 38.0 μM for HIV-1 replication. GB-1a can block the conversion of HIV-1 genomic RNA to DNA and can be used in research related to AIDS (HIV-1 infection). GB-1a can be naturally extracted from the heartwood of Garcinia multiflora Champ .
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